Tranexamic acid

Product Name: Tranexamic acid
CAS No.: 1197-18-8
MF: C8H15NO2
MW: 157.21
Melting point: >300 °C (lit.)
Storage temp.: 2-8°C
Solubility: Freely soluble in water and in glacial acetic acid, practically insoluble in acetone and in ethanol (96 per cent).
Form: Crystalline Powder
Color: white to off-white
Standard: BP

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Description

Used as lysine analogue to characterize binding sites in plasminogen. The cleavage of fibrin by plasmin, is a normal step in the dissolution of fibrin clots after wound repair. Tranexamic acid is an inhibitor of fibrinolysis that blocks the interaction of plasmin with fibrin (IC50 = 3.1 μM). It is a lysine mimetic that binds the lysine binding site in plasmin. Antifibrinolytic agents have value when fibrinolytic activity is abnormally high or when coagulation is impaired.