Toltrazuril

Product Name: Toltrazuril
CAS No.: 69004-03-1
MF: C18H14F3N3O4S
MW: 425.38
Melting point: 194-196°C
Storage temp.: 2-8°C
Solubility: Toltrazuril is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of toltrazuril in ethanol is approximately 1 mg/ml and approximately 25 mg/ml in DMSO and DMF.
Form: powder
Color: white to off-white
Standard: In-house

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Description

Toltrazuril is an antiprotozoal agent that may be considered as an alternative treatment for coccidiosis in dogs and cats, Hepatazoon infections, or for treating the oocyst shedding stage of toxoplasmosis in cats. It has also been used as a treatment for overwhelming parasitic loads in lizards (Bearded Dragons).
Toltrazuril has activity against parasites of the genus Hepatozoon, but other drugs (e.g., imidocarb, primaquine, doxycycline) are generally used.
While toltrazuril has been used to treat equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona, use of approved products now available (e.g., nitazoxanide, ponazuril, pyrimethamine/ sulfadiazine) is preferred.