Azithromycin

Product Name: Azithromycin
CAS No.: 83905-01-5
MF: C38H72N2O12
MW: 748.98
Melting point: 113-115°C
Storage temp.: Sealed in dry,2-8°C
Solubility: Practically insoluble in water, freely soluble in anhydrous ethanol and in methylene chloride.
Form: Crystals or Crystalline Powder
Color: White to off-white
Density: 1.18±0.1 g/cm3(Predicted)
Standard: EP/USP

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Description

Azithromycin is a semi-synthetic, ring-expanded erythromycin, produced by a Beckmann rearrangement of erythromycin oxime and reduction to the imine ether, followed by reductive methylation. Azithromycin was the first of the azalides and was designed to improve stability and biological half-life of erythromycin A, as well as improve activity against Gram negative bacteria. Since its discovery in 1980 by Djokic and co-workers, azithromycin has enjoyed considerable therapeutic success.